All six of the NFL teams playing on Thanksgiving will be without critical players. The Chicago Bears will be without center Ryan Bates (concussion). The Detroit Lions will be without cornerback Carlton Davis III (knee/thumb) and left tackle Taylor Decker (knee).

The San Francisco 49ers are reeling and now head to Buffalo for a prime time game. Will they have their starting QB back in the fold?

San Francisco 49ers quarterback Brock Purdy was limited with the right shoulder injury that sidelined him last week and there is growing concern about the long-term status of left tackle Trent Williams.