The Dallas Cowboys and San Francisco 49ers have both been titans of the NFC the past few seasons, but have seen a free fall ...

Five San Francisco 49ers found their way among the top Pro Bowl fan voting recipients in Monday's current top 10 announcement ...

San Francisco 49ers offensive tackle Trent Williams and his wife are mourning the stillbirth of their baby named Trenton ...

The San Francisco 49ers hosted a fan-focused event with the 49ers Pride Fan Group and PLUS (LGBTQ+) ERG to discuss being out ...

San Francisco 49ers running back Christian McCaffrey suffered a knee injury and limped to the locker room in the second ...

The Buffalo Bills won the turnover battle for the 10th time in 12 games in their rout of the San Francisco 49ers on Sunday ...

The San Francisco 49ers dropped their record to 5-7 after a 35-10 loss against the Buffalo Bills in Week 13. Today, Pro ...

The Bills sacked Purdy twice, Greg Rousseau getting one while the other was called a team sack because Purdy lost a fumble ...

The San Francisco 49ers suffered another crushing defeat, this time in a snowy showdown against the Buffalo Bills. The 35-10 ...

The 49ers’ third straight defeat came in 35-10 fashion to the AFC East-clinching Buffalo Bills amid a snowstorm at Highmark ...

The 49ers season is still trending down and now they're searching for answers on if they can get back on track.

Standout linebacker Fred Warner exited the San Francisco 49ers' Sunday Night Football contest at the Buffalo Bills during the ...